Human SNX1 activation kit by CRISPRa

CAT#: GA104553

SNX1 CRISPRa kit - CRISPR gene activation of human sorting nexin 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SNX1
• Locus ID: 6642
• Kit Components:

  GA104553G1, SNX1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104553G2, SNX1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104553G3, SNX1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001242933, NM_003099, NM_148955, NM_152826
• Synonyms: HsT17379; VPS5
• Summary: 'This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]'