Human SON activation kit by CRISPRa

CAT#: GA104561

SON CRISPRa kit - CRISPR gene activation of human SON DNA binding protein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SON
• Locus ID: 6651
• Kit Components:

  GA104561G1, SON gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104561G2, SON gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104561G3, SON gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001291411, NM_001291412, NM_003103, NM_032195, NM_058183, NM_138925, NM_138926, NM_138927, NR_103796, NR_103797, NR_103798
• Synonyms: BASS1; C21orf50; DBP-5; NREBP; SON3
• Summary: 'This gene encodes a protein that contains multiple simple repeats. The encoded protein binds RNA and promotes pre-mRNA splicing, particularly of transcripts with poor splice sites. The protein also recognizes a specific DNA sequence found in the human hepatitis B virus (HBV) and represses HBV core promoter activity. There is a pseudogene for this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]'