Human SOX1 activation kit by CRISPRa

CAT#: GA104566

SOX1 CRISPRa kit - CRISPR gene activation of human SRY-box transcription factor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SOX1
• Locus ID: 6656
• Kit Components:

  GA104566G1, SOX1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104566G2, SOX1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104566G3, SOX1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005986
• Synonyms: SRY (sex determining region Y)-box 1; SRY-related HMG-box gene 1
• Summary: 'This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development. [provided by RefSeq, Jul 2008]'