Human SOX4 activation kit by CRISPRa

CAT#: GA104569

SOX4 CRISPRa kit - CRISPR gene activation of human SRY-box transcription factor 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SOX4
• Locus ID: 6659
• Kit Components:

  GA104569G1, SOX4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104569G2, SOX4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104569G3, SOX4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003107
• Synonyms: EVI16
• Summary: 'This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. [provided by RefSeq, Jul 2008]'