Human SPG7 activation kit by CRISPRa

CAT#: GA104587

SPG7 CRISPRa kit - CRISPR gene activation of human SPG7 matrix AAA peptidase subunit, paraplegin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SPG7
• Locus ID: 6687
• Kit Components:

  GA104587G1, SPG7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104587G2, SPG7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104587G3, SPG7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003119, NM_199367, NM_001363850
• Synonyms: CAR; CMAR; PGN; SPG5C
• Summary: 'This gene encodes a mitochondrial metalloprotease protein that is a member of the AAA family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Mutations in this gene cause autosomal recessive spastic paraplegia 7. Two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2014]'