Human SPR activation kit by CRISPRa

CAT#: GA104597

SPR CRISPRa kit - CRISPR gene activation of human sepiapterin reductase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SPR
• Locus ID: 6697
• Kit Components:

  GA104597G1, SPR gRNA vector 1 in pCas-Guide-CRISPRa

  GA104597G2, SPR gRNA vector 2 in pCas-Guide-CRISPRa

  GA104597G3, SPR gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003124
• Synonyms: SDR38C1
• Summary: This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1. [provided by RefSeq, Jul 2008]