Human SRD5A2 activation kit by CRISPRa

CAT#: GA104615

SRD5A2 CRISPRa kit - CRISPR gene activation of human steroid 5 alpha-reductase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SRD5A2
• Locus ID: 6716
• Kit Components:

  GA104615G1, SRD5A2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104615G2, SRD5A2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104615G3, SRD5A2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000348
• Synonyms: MGC138457
• Summary: 'This gene encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH). [provided by RefSeq, Jul 2008]'