Human SR1 (SRI) activation kit by CRISPRa

CAT#: GA104616

SRI CRISPRa kit - CRISPR gene activation of human sorcin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SRI
• Locus ID: 6717
• Kit Components:

  GA104616G1, SR1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104616G2, SR1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104616G3, SR1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001256891, NM_001256892, NM_003130, NM_198901
• Synonyms: CP-22; CP22; SCN; V19
• Summary: 'This gene encodes a calcium-binding protein with multiple E-F hand domains that relocates from the cytoplasm to the sarcoplasmic reticulum in response to elevated calcium levels. In addition to regulating intracellular calcium homeostasis it also modulates excitation-contraction coupling in the heart. Alternative splicing results in multiple transcript variants encoding distinct proteins. Multiple pseudogenes exist for this gene. [provided by RefSeq, Mar 2012]'