Human AKR1D1 activation kit by CRISPRa

CAT#: GA104617

AKR1D1 CRISPRa kit - CRISPR gene activation of human aldo-keto reductase family 1 member D1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AKR1D1
• Locus ID: 6718
• Kit Components:

  GA104617G1, AKR1D1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA104617G2, AKR1D1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA104617G3, AKR1D1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001190906, NM_001190907, NM_005989
• Synonyms: 3o5bred; CBAS2; SRD5B1
• Summary: The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet. [provided by RefSeq, Jul 2010]