Human SRPK1 activation kit by CRISPRa

CAT#: GA104629

SRPK1 CRISPRa kit - CRISPR gene activation of human SRSF protein kinase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SRPK1
• Locus ID: 6732
• Kit Components:

  GA104629G1, SRPK1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104629G2, SRPK1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104629G3, SRPK1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003137, NR_034069
• Synonyms: SFRSK1
• Summary: 'This gene encodes a serine/arginine protein kinase specific for the SR (serine/arginine-rich domain) family of splicing factors. The protein localizes to the nucleus and the cytoplasm. It is thought to play a role in regulation of both constitutive and alternative splicing by regulating intracellular localization of splicing factors. Alternative splicing of this gene results in multiple transcript variants. Additional alternatively spliced transcript variants have been described for this gene, but their full length nature have not been determined.[provided by RefSeq, Jul 2010]'