Human Somatostatin (SST) activation kit by CRISPRa

CAT#: GA104643

SST CRISPRa kit - CRISPR gene activation of human somatostatin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SST
• Locus ID: 6750
• Kit Components:

  GA104643G1, Somatostatin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104643G2, Somatostatin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104643G3, Somatostatin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001048
• Synonyms: SMST
• Summary: 'The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells. [provided by RefSeq, Jul 2008]'