Human Somatostatin Receptor 1 (SSTR1) activation kit by CRISPRa

CAT#: GA104644

SSTR1 CRISPRa kit - CRISPR gene activation of human somatostatin receptor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SSTR1
• Locus ID: 6751
• Kit Components:

  GA104644G1, Somatostatin Receptor 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104644G2, Somatostatin Receptor 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104644G3, Somatostatin Receptor 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001049
• Synonyms: SRIF-2; SS-1-R; SS1-R; SS1R
• Summary: 'Somatostatins are peptide hormones that regulate diverse cellular functions such as neurotransmission, cell proliferation, and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins. Somatostatin has two active forms of 14 and 28 amino acids. The biological effects of somatostatins are mediated by a family of G-protein coupled somatostatin receptors that are expressed in a tissue-specific manner. The protein encoded by this gene is a member of the superfamily of somatostatin receptors having seven transmembrane segments. Somatostatin receptors form homodimers and heterodimers with other members of the superfamily as well as with other G-protein coupled receptors and receptor tyrosine kinases. This somatostatin receptor has greater affinity for somatostatin-14 than -28. [provided by RefSeq, Jul 2012]'