Human NEK4 activation kit by CRISPRa

CAT#: GA104673

NEK4 CRISPRa kit - CRISPR gene activation of human NIMA related kinase 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NEK4
• Locus ID: 6787
• Kit Components:

  GA104673G1, NEK4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104673G2, NEK4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104673G3, NEK4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001193533, NM_003157, NM_001348412, NM_001348413, NM_001348414
• Synonyms: NRK2; pp12301; STK2
• Summary: 'The protein encoded by this gene is a serine/threonine protein kinase required for normal entry into replicative senescence. The encoded protein also is involved in cell cycle arrest in response to double-stranded DNA damage. Finally, this protein plays a role in maintaining cilium integrity, and defects in this gene have been associated with ciliopathies. [provided by RefSeq, Jan 2017]'