Human CDKL5 activation kit by CRISPRa

CAT#: GA104677

CDKL5 CRISPRa kit - CRISPR gene activation of human cyclin dependent kinase like 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CDKL5
• Locus ID: 6792
• Kit Components:

  GA104677G1, CDKL5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104677G2, CDKL5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104677G3, CDKL5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001037343, NM_003159, NM_001323289
• Synonyms: CFAP247; EIEE2; ISSX; STK9
• Summary: 'This gene is a member of Ser/Thr protein kinase family and encodes a phosphorylated protein with protein kinase activity. Mutations in this gene have been associated with X-linked infantile spasm syndrome (ISSX), also known as X-linked West syndrome, and Rett syndrome (RTT). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]'