Human Syntaxin 5A (STX5) activation kit by CRISPRa

CAT#: GA104686

STX5 CRISPRa kit - CRISPR gene activation of human syntaxin 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: STX5
• Locus ID: 6811
• Kit Components:

  GA104686G1, STX5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA104686G2, STX5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA104686G3, STX5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001244666, NM_001330294, NM_003164
• Synonyms: SED5; STX5A
• Summary: This gene encodes a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for v-SNAREs (vesicle-SNAP receptors), permitting specific synaptic vesicle docking and fusion. The encoded protein regulates endoplasmic reticulum to Golgi transport and plays a critical role in autophagy. Autoantibodies targeting the encoded protein may be a diagnostic marker for endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]