Human Munc18 1 (STXBP1) activation kit by CRISPRa

CAT#: GA104687

STXBP1 CRISPRa kit - CRISPR gene activation of human syntaxin binding protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: STXBP1
• Locus ID: 6812
• Kit Components:

  GA104687G1, Munc18 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104687G2, Munc18 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104687G3, Munc18 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001032221, NM_003165
• Synonyms: MUNC18-1; NSEC1; P67; RBSEC1; UNC18
• Summary: 'This gene encodes a syntaxin-binding protein. The encoded protein appears to play a role in release of neurotransmitters via regulation of syntaxin, a transmembrane attachment protein receptor. Mutations in this gene have been associated with infantile epileptic encephalopathy-4. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010]'