Human CSPS (SULT1A3) activation kit by CRISPRa

CAT#: GA104692

SULT1A3 CRISPRa kit - CRISPR gene activation of human sulfotransferase family 1A member 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SULT1A3
• Locus ID: 6818
• Kit Components:

  GA104692G1, CSPS gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104692G2, CSPS gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104692G3, CSPS gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001017387, NM_003166, NM_177552
• Synonyms: HAST; HAST3; M-PST; MGC117469; ST1A5; STM; SULT1A4; TL-PST
• Summary: 'Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a phenol sulfotransferase with thermolabile enzyme activity. Four sulfotransferase genes are located on the p arm of chromosome 16; this gene and SULT1A4 arose from a segmental duplication. This gene is the most centromeric of the four sulfotransferase genes. Read-through transcription exists between this gene and the upstream SLX1A (SLX1 structure-specific endonuclease subunit homolog A) gene that encodes a protein containing GIY-YIG domains. [provided by RefSeq, Nov 2010]'