Human SURF4 activation kit by CRISPRa

CAT#: GA104704

SURF4 CRISPRa kit - CRISPR gene activation of human surfeit 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SURF4
• Locus ID: 6836
• Kit Components:

  GA104704G1, SURF4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104704G2, SURF4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104704G3, SURF4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001280788, NM_001280789, NM_001280790, NM_001280791, NM_001280792, NM_001280793, NM_033161
• Synonyms: ERV29
• Summary: 'This gene is located in the surfeit gene cluster, which is comprised of very tightly linked housekeeping genes that do not share sequence similarity. The encoded protein is a conserved integral membrane protein that interacts with endoplasmic reticulum-Golgi intermediate compartment proteins. Disruption of this gene results in reduced numbers of endoplasmic reticulum-Golgi intermediate compartment clusters and redistribution of coat protein I to the cytosol. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]'