Human VAMP1 activation kit by CRISPRa

CAT#: GA104709

VAMP1 CRISPRa kit - CRISPR gene activation of human vesicle associated membrane protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: VAMP1
• Locus ID: 6843
• Kit Components:

  GA104709G1, VAMP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104709G2, VAMP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104709G3, VAMP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001297438, NM_014231, NM_016830, NM_199245, NR_123717
• Synonyms: SPAX1; SYB1; VAMP-1
• Summary: 'Synapotobrevins, syntaxins, and the synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Mutations in this gene are associated with autosomal dominant spastic ataxia 1. Multiple alternative splice variants have been described, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2014]'