Human SYK activation kit by CRISPRa

CAT#: GA104714

SYK CRISPRa kit - CRISPR gene activation of human spleen associated tyrosine kinase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SYK
• Locus ID: 6850
• Kit Components:

  GA104714G1, SYK gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104714G2, SYK gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104714G3, SYK gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001135052, NM_001174167, NM_001174168, NM_003177, NR_024155, NR_024156
• Synonyms: p72-Syk
• Summary: 'This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]'