Human TAC1 activation kit by CRISPRa

CAT#: GA104723

TAC1 CRISPRa kit - CRISPR gene activation of human tachykinin precursor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TAC1
• Locus ID: 6863
• Kit Components:

  GA104723G1, TAC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104723G2, TAC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104723G3, TAC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003182, NM_013996, NM_013997, NM_013998
• Synonyms: Hs.2563; NK2; NKNA; NPK; TAC2
• Summary: 'This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Substance P is an antimicrobial peptide with antibacterial and antifungal properties. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]'