Human TAT activation kit by CRISPRa

CAT#: GA104754

TAT CRISPRa kit - CRISPR gene activation of human tyrosine aminotransferase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TAT
• Locus ID: 6898
• Kit Components:

  GA104754G1, TAT gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104754G2, TAT gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104754G3, TAT gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000353
• Synonyms: tyrosine aminotransferase; tyrosine aminotransferase, cytosolic
• Summary: 'This nuclear gene encodes a mitochondrial protein tyrosine aminotransferase which is present in the liver and catalyzes the conversion of L-tyrosine into p-hydroxyphenylpyruvate. Mutations in this gene cause tyrosinemia (type II, Richner-Hanhart syndrome), a disorder accompanied by major skin and corneal lesions, with possible cognitive disability. A regulator gene for tyrosine aminotransferase is X-linked. [provided by RefSeq, Jul 2008]'