Human T box 2 (TBX2) activation kit by CRISPRa

CAT#: GA104765

TBX2 CRISPRa kit - CRISPR gene activation of human T-box transcription factor 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TBX2
• Locus ID: 6909
• Kit Components:

  GA104765G1, T box 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104765G2, T box 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104765G3, T box 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005994
• Synonyms: FLJ10169
• Summary: 'This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. Transcript heterogeneity due to alternative polyadenylation has been noted for this gene. [provided by RefSeq, Jul 2008]'