Human TFIIS (TCEA2) activation kit by CRISPRa

CAT#: GA104773

TCEA2 CRISPRa kit - CRISPR gene activation of human transcription elongation factor A2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TCEA2
• Locus ID: 6919
• Kit Components:

  GA104773G1, TFIIS gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104773G2, TFIIS gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104773G3, TFIIS gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003195, NM_198723
• Synonyms: TFIIS
• Summary: 'The protein encoded by this gene is found in the nucleus, where it functions as an SII class transcription elongation factor. Elongation factors in this class are responsible for releasing RNA polymerase II ternary complexes from transcriptional arrest at template-encoded arresting sites. The encoded protein has been shown to interact with general transcription factor IIB, a basal transcription factor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]'