Human TBX3 activation kit by CRISPRa

CAT#: GA104779

TBX3 CRISPRa kit - CRISPR gene activation of human T-box transcription factor 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TBX3
• Locus ID: 6926
• Kit Components:

  GA104779G1, TBX3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104779G2, TBX3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104779G3, TBX3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005996, NM_016569
• Synonyms: TBX3-ISO; UMS; XHL
• Summary: 'This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined. [provided by RefSeq, Jul 2008]'