Human MLX activation kit by CRISPRa

CAT#: GA104794

MLX CRISPRa kit - CRISPR gene activation of human MAX dimerization protein MLX

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MLX
• Locus ID: 6945
• Kit Components:

  GA104794G1, MLX gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104794G2, MLX gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104794G3, MLX gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_013383, NM_170607, NM_170608, NM_198204, NM_198205
• Synonyms: bHLHd13; MAD7; MXD7; TCFL4
• Summary: 'The product of this gene belongs to the family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors. These factors form heterodimers with Mad proteins and play a role in proliferation, determination and differentiation. This gene product may act to diversify Mad family function by its restricted association with a subset of the Mad family of transcriptional repressors, namely, Mad1 and Mad4. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]'