Human DYNLT3 activation kit by CRISPRa

CAT#: GA104806

DYNLT3 CRISPRa kit - CRISPR gene activation of human dynein light chain Tctex-type 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DYNLT3
• Locus ID: 6990
• Kit Components:

  GA104806G1, DYNLT3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104806G2, DYNLT3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104806G3, DYNLT3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006520
• Synonyms: RP3; TCTE1L; TCTEX1L
• Summary: 'This gene encodes a member of a subclass of dynein light chains. The encoded protein homodimerizes and forms the light chain component of the cytoplasmic dynein motor protein complex. This protein may be important for binding dynein to specific cargos including the spindle checkpoint protein BUB3. This protein may also function independently of dynein as a transcriptional modulator. Pseudogenes of this gene are found on chromosomes 2 and 20.[provided by RefSeq, Mar 2010]'