Human mtTFA (TFAM) activation kit by CRISPRa

CAT#: GA104828

TFAM CRISPRa kit - CRISPR gene activation of human transcription factor A, mitochondrial

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TFAM
• Locus ID: 7019
• Kit Components:

  GA104828G1, mtTFA gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104828G2, mtTFA gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104828G3, mtTFA gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001270782, NM_003201, NM_012251, NR_073073
• Synonyms: MTTF1; MTTFA; TCF6; TCF6L1; TCF6L2; TCF6L3
• Summary: 'This gene encodes a key mitochondrial transcription factor containing two high mobility group motifs. The encoded protein also functions in mitochondrial DNA replication and repair. Sequence polymorphisms in this gene are associated with Alzheimer's and Parkinson's diseases. There are pseudogenes for this gene on chromosomes 6, 7, and 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]'