Human CP2c (TFCP2) activation kit by CRISPRa

CAT#: GA104833

TFCP2 CRISPRa kit - CRISPR gene activation of human transcription factor CP2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TFCP2
• Locus ID: 7024
• Kit Components:

  GA104833G1, CP2c gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104833G2, CP2c gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104833G3, CP2c gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001173452, NM_001173453, NM_005653
• Synonyms: LBP1C; LSF; LSF1D; SEF; TFCP2C
• Summary: 'This gene encodes a transcription factor that binds the alpha-globin promoter and activates transcription of the alpha-globin gene. The encoded protein regulates erythroid gene expression, plays a role in the transcriptional switch of globin gene promoters, and it activates many other cellular and viral gene promoters. The gene product interacts with certain inflammatory response factors, and polymorphisms of this gene may be involved in the pathogenesis of Alzheimer's disease. [provided by RefSeq, Mar 2010]'