Human Spasmolytic Polypeptide (TFF2) activation kit by CRISPRa

CAT#: GA104840

TFF2 CRISPRa kit - CRISPR gene activation of human trefoil factor 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TFF2
• Locus ID: 7032
• Kit Components:

  GA104840G1, Spasmolytic Polypeptide gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104840G2, Spasmolytic Polypeptide gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104840G3, Spasmolytic Polypeptide gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005423
• Synonyms: SML1; SP
• Summary: 'Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. The encoded protein inhibits gastric acid secretion. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008]'