Human Trefoil Factor 3 (TFF3) activation kit by CRISPRa

CAT#: GA104841

TFF3 CRISPRa kit - CRISPR gene activation of human trefoil factor 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TFF3
• Locus ID: 7033
• Kit Components:

  GA104841G1, Trefoil Factor 3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104841G2, Trefoil Factor 3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104841G3, Trefoil Factor 3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003226
• Synonyms: ITF; P1B; TFI
• Summary: 'Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. This gene is expressed in goblet cells of the intestines and colon. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008]'