Human Transferrin Receptor 2 (TFR2) activation kit by CRISPRa

CAT#: GA104843

TFR2 CRISPRa kit - CRISPR gene activation of human transferrin receptor 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TFR2
• Locus ID: 7036
• Kit Components:

  GA104843G1, Transferrin Receptor 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104843G2, Transferrin Receptor 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104843G3, Transferrin Receptor 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001206855, NM_003227
• Synonyms: HFE3; TFRC2
• Summary: 'This gene encodes a single-pass type II membrane protein, which is a member of the transferrin receptor-like family. This protein mediates cellular uptake of transferrin-bound iron, and may be involved in iron metabolism, hepatocyte function and erythrocyte differentiation. Mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]'