Human CD71 (TFRC) activation kit by CRISPRa

CAT#: GA104844

TFRC CRISPRa kit - CRISPR gene activation of human transferrin receptor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TFRC
• Locus ID: 7037
• Kit Components:

  GA104844G1, CD71 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104844G2, CD71 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104844G3, CD71 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001128148, NM_001313965, NM_001313966, NM_003234
• Synonyms: CD71; IMD46; p90; T9; TFR; TFR1; TR; TRFR
• Summary: 'This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015]'