Human TGF alpha (TGFA) activation kit by CRISPRa

CAT#: GA104846

TGFA CRISPRa kit - CRISPR gene activation of human transforming growth factor alpha

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TGFA
• Locus ID: 7039
• Kit Components:

  GA104846G1, TGFA gRNA vector 1 in pCas-Guide-CRISPRa

  GA104846G2, TGFA gRNA vector 2 in pCas-Guide-CRISPRa

  GA104846G3, TGFA gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001099691, NM_001308158, NM_001308159, NM_003236
• Synonyms: TFGA
• Summary: This gene encodes a growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This protein may act as either a transmembrane-bound ligand or a soluble ligand. This gene has been associated with many types of cancers, and it may also be involved in some cases of cleft lip/palate. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]