Human TGM1 activation kit by CRISPRa

CAT#: GA104858

TGM1 CRISPRa kit - CRISPR gene activation of human transglutaminase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TGM1
• Locus ID: 7051
• Kit Components:

  GA104858G1, TGM1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104858G2, TGM1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104858G3, TGM1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000359
• Synonyms: ARCI1; ICR2; KTG; LI; LI1; TGASE; TGK
• Summary: 'The protein encoded by this gene is a membrane protein that catalyzes the addition of an alkyl group from an akylamine to a glutamine residue of a protein, forming an alkylglutamine in the protein. This protein alkylation leads to crosslinking of proteins and catenation of polyamines to proteins. This gene contains either one or two copies of a 22 nt repeat unit in its 3' UTR. Mutations in this gene have been associated with autosomal recessive lamellar ichthyosis (LI) and nonbullous congenital ichthyosiform erythroderma (NCIE). [provided by RefSeq, Jul 2008]'