Human Transglutaminase 3 (TGM3) activation kit by CRISPRa

CAT#: GA104860

TGM3 CRISPRa kit - CRISPR gene activation of human transglutaminase 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TGM3
• Locus ID: 7053
• Kit Components:

  GA104860G1, Transglutaminase 3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104860G2, Transglutaminase 3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104860G3, Transglutaminase 3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003245, N23065
• Synonyms: TGE
• Summary: 'Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene consists of two polypeptide chains activated from a single precursor protein by proteolysis. The encoded protein is involved the later stages of cell envelope formation in the epidermis and hair follicle. [provided by RefSeq, Jul 2008]'