Human Thimet Oligopeptidase (THOP1) activation kit by CRISPRa

CAT#: GA104868

THOP1 CRISPRa kit - CRISPR gene activation of human thimet oligopeptidase 1


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol THOP1
Locus ID 7064
Kit Components

GA104868G1, THOP1 gRNA vector 1 in pCas-Guide-CRISPRa

GA104868G2, THOP1 gRNA vector 2 in pCas-Guide-CRISPRa

GA104868G3, THOP1 gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_003249
Synonyms EP24.15; MEPD_HUMAN; MP78; TOP
Summary The protein encoded by this gene is a kininase that uses zinc as a cofactor. The encoded oligopeptidase cleaves cytosolic peptides, making them unavailable for display on antigen-presenting cells. This protein also cleaves neuropeptides under 20 aa in length and can degrade beta-amyloid precursor protein to amyloidogenic peptides. [provided by RefSeq, Nov 2015]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.