Human TRAF5 activation kit by CRISPRa

CAT#: GA104970

TRAF5 CRISPRa kit - CRISPR gene activation of human TNF receptor associated factor 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TRAF5
• Locus ID: 7188
• Kit Components:

  GA104970G1, TRAF5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA104970G2, TRAF5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA104970G3, TRAF5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001033910, NM_001319207, NM_004619, NM_145759
• Synonyms: MGC:39780; RNF84
• Summary: The scaffold protein encoded by this gene is a member of the tumor necrosis factor receptor-associated factor (TRAF) protein family and contains a meprin and TRAF homology (MATH) domain, a RING-type zinc finger, and two TRAF-type zinc fingers. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein is one of the components of a multiple protein complex which binds to tumor necrosis factor (TNF) receptor cytoplasmic domains and mediates TNF-induced activation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]