Human TRIO activation kit by CRISPRa

CAT#: GA104975

TRIO CRISPRa kit - CRISPR gene activation of human trio Rho guanine nucleotide exchange factor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TRIO
• Locus ID: 7204
• Kit Components:

  GA104975G1, TRIO gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104975G2, TRIO gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104975G3, TRIO gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_007118, NR_134469
• Synonyms: ARHGEF23; MEBAS; MRD44; tgat
• Summary: 'This gene encodes a large protein that functions as a GDP to GTP exchange factor. This protein promotes the reorganization of the actin cytoskeleton, thereby playing a role in cell migration and growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]'