Human TRIP6 activation kit by CRISPRa

CAT#: GA104976

TRIP6 CRISPRa kit - CRISPR gene activation of human thyroid hormone receptor interactor 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TRIP6
• Locus ID: 7205
• Kit Components:

  GA104976G1, TRIP6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104976G2, TRIP6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104976G3, TRIP6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003302
• Synonyms: OIP-1; OIP1; TRIP-6; TRIP6i2; ZRP-1
• Summary: 'This gene is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]'