Human TRPC5 activation kit by CRISPRa

CAT#: GA104981

TRPC5 CRISPRa kit - CRISPR gene activation of human transient receptor potential cation channel subfamily C member 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TRPC5
• Locus ID: 7224
• Kit Components:

  GA104981G1, TRPC5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104981G2, TRPC5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104981G3, TRPC5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_012471
• Synonyms: PPP1R159; TRP5
• Summary: 'This gene belongs to the transient receptor family. It encodes one of the seven mammalian TRPC (transient receptor potential channel) proteins. The encoded protein is a multi-pass membrane protein and is thought to form a receptor-activated non-selective calcium permeant cation channel. The protein is active alone or as a heteromultimeric assembly with TRPC1, TRPC3, and TRPC4. It also interacts with multiple proteins including calmodulin, CABP1, enkurin, Na(+)-H+ exchange regulatory factor (NHERF ), interferon-induced GTP-binding protein (MX1), ring finger protein 24 (RNF24), and SEC14 domain and spectrin repeat-containing protein 1 (SESTD1). [provided by RefSeq, May 2010]'