Human TSSC3 (PHLDA2) activation kit by CRISPRa

CAT#: GA104998

PHLDA2 CRISPRa kit - CRISPR gene activation of human pleckstrin homology like domain family A member 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PHLDA2
• Locus ID: 7262
• Kit Components:

  GA104998G1, TSSC3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104998G2, TSSC3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104998G3, TSSC3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003311
• Synonyms: BRW1C; BWR1C; HLDA2; IPL; TSSC3
• Summary: 'This gene is located in a cluster of imprinted genes on chromosome 11p15.5, which is considered to be an important tumor suppressor gene region. Alterations in this region may be associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene has been shown to be imprinted, with preferential expression from the maternal allele in placenta and liver. [provided by RefSeq, Oct 2010]'