Human MMS2 (UBE2V2) activation kit by CRISPRa

CAT#: GA105053

UBE2V2 CRISPRa kit - CRISPR gene activation of human ubiquitin conjugating enzyme E2 V2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: UBE2V2
• Locus ID: 7336
• Kit Components:

  GA105053G1, MMS2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105053G2, MMS2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105053G3, MMS2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003350
• Synonyms: DDVit-1; DDVIT1; EDAF-1; EDPF-1; EDPF1; MMS2; UEV-2; UEV2
• Summary: 'Ubiquitin-conjugating enzyme E2 variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene also shares homology with ubiquitin-conjugating enzyme E2 variant 1 and yeast MMS2 gene product. It may be involved in the differentiation of monocytes and enterocytes. [provided by RefSeq, Jul 2008]'