Human UCHL3 activation kit by CRISPRa

CAT#: GA105059

UCHL3 CRISPRa kit - CRISPR gene activation of human ubiquitin C-terminal hydrolase L3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: UCHL3
• Locus ID: 7347
• Kit Components:

  GA105059G1, UCHL3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105059G2, UCHL3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105059G3, UCHL3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001270952, NM_006002
• Synonyms: UCH-L3
• Summary: The protein encoded by this gene is a member of the deubiquitinating enzyme family. Members of this family are proteases that catalyze the removal of ubiquitin from polypeptides and are divided into five classes, depending on the mechanism of catalysis. This protein may hydrolyze the ubiquitinyl-N-epsilon amide bond of ubiquitinated proteins to regenerate ubiquitin for another catalytic cycle. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012]