Human UGT2B7 activation kit by CRISPRa

CAT#: GA105072

UGT2B7 CRISPRa kit - CRISPR gene activation of human UDP glucuronosyltransferase family 2 member B7

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: UGT2B7
• Locus ID: 7364
• Kit Components:

  GA105072G1, UGT2B7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105072G2, UGT2B7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105072G3, UGT2B7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001074, NM_001330719, NM_001349568
• Synonyms: UDPGT2B7; UDPGT 2B9; UDPGTH2; UGT2B9
• Summary: 'The protein encoded by this gene belongs to the UDP-glycosyltransferase (UGT) family. UGTs serve a major role in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This protein is localized in the microsome membrane, and has unique specificity for 3,4-catechol estrogens and estriol, suggesting that it may play an important role in regulating the level and activity of these potent estrogen metabolites. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2017]'