Human UGT2B17 activation kit by CRISPRa

CAT#: GA105075

UGT2B17 CRISPRa kit - CRISPR gene activation of human UDP glucuronosyltransferase family 2 member B17

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: UGT2B17
• Locus ID: 7367
• Kit Components:

  GA105075G1, UGT2B17 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105075G2, UGT2B17 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105075G3, UGT2B17 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001077
• Synonyms: BMND12; UDPGT2B17
• Summary: 'This gene encodes a member of the uridine diphosphoglucuronosyltransferase protein family. The encoded enzyme catalyzes the transfer of glucuronic acid from uridine diphosphoglucuronic acid to a diverse array of substrates including steroid hormones and lipid-soluble drugs. This process, known as glucuronidation, is an intermediate step in the metabolism of steroids. Copy number variation in this gene is associated with susceptibility to osteoporosis.[provided by RefSeq, Apr 2010]'