Human UMPS activation kit by CRISPRa

CAT#: GA105079

UMPS CRISPRa kit - CRISPR gene activation of human uridine monophosphate synthetase

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Find the corresponding CRISPRi Inhibitor Kit

USD 1,290.00

2 Weeks*

Size
    • 1 kit

Product Images

Frequently bought together (2)
Rabbit Polyclonal Anti-UMPS Antibody
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qSTAR qPCR primer pairs against Homo sapiens gene UMPS
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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol UMPS
Locus ID 7372
Kit Components

GA105079G1, UMPS gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105079G2, UMPS gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105079G3, UMPS gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_000373, NR_033434, NR_033437
Synonyms OPRT
Summary 'This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]'

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.