Human UROD activation kit by CRISPRa

CAT#: GA105092

UROD CRISPRa kit - CRISPR gene activation of human uroporphyrinogen decarboxylase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: UROD
• Locus ID: 7389
• Kit Components:

  GA105092G1, UROD gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105092G2, UROD gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105092G3, UROD gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000374, NR_036510, NR_158185, NR_158184
• Synonyms: PCT; UPD
• Summary: 'This gene encodes an enzyme in the heme biosynthetic pathway. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. Mutations and deficiency in this enzyme are known to cause familial porphyria cutanea tarda and hepatoerythropoetic porphyria.[provided by RefSeq, Aug 2010]'