Human KDM6A activation kit by CRISPRa

CAT#: GA105100

KDM6A CRISPRa kit - CRISPR gene activation of human lysine demethylase 6A

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KDM6A
• Locus ID: 7403
• Kit Components:

  GA105100G1, KDM6A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105100G2, KDM6A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105100G3, KDM6A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001291415, NM_001291416, NM_001291417, NM_001291418, NM_001291421, NM_021140, NR_111960
• Synonyms: bA386N14.2; KABUK2; UTX
• Summary: 'This gene is located on the X chromosome and is the corresponding locus to a Y-linked gene which encodes a tetratricopeptide repeat (TPR) protein. The encoded protein of this gene contains a JmjC-domain and catalyzes the demethylation of tri/dimethylated histone H3. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2014]'