Human PFDN3 (VBP1) activation kit by CRISPRa

CAT#: GA105107

VBP1 CRISPRa kit - CRISPR gene activation of human VHL binding protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: VBP1
• Locus ID: 7411
• Kit Components:

  GA105107G1, VBP1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105107G2, VBP1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105107G3, VBP1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001303543, NM_001303544, NM_001303545, NM_003372
• Synonyms: HIBBJ46; PFD3; PFDN3; VBP-1
• Summary: The protein encoded by this gene interacts with the Von Hippel-Lindau protein to form an intracellular complex. The encoded protein functions as a chaperone protein, and may play a role in the transport of the Von Hippel-Lindau protein from the perinuclear granules to the nucleus or cytoplasm. Alternative splicing and the use of alternate transcription start sites results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Jan 2015]